Currently, PI System thick clients such as PI DataLink or PI ProcessBook are not tested against virtualized environments, as described in KB01590. However, there are various benefits of virtualizing parts of the PI System, as outlined in the article. As a sysadmin, I would like official support for virtualizing PI System clients using technologies such as App-V or Citrix Virtual Apps (formerly ZenApp) in order to realize these benefits across our company’s technology stack.

https://customers.osisoft.com/s/knowledgearticle?knowledgeArticleUrl=KB01590